Methyl 1,2,5,6-tetrahydro-1-methylnicotinate - Names and Identifiers
Name | Arecoline
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Synonyms | Arecolin Arekolin Arecaline NSC 56321 Arecoline arecoline CCRIS 7688 Arecholine BRN 0123045 Arecoline base UNII-4ALN5933BH Methylarecaiden Methyl arecaidin Arecaidine methyl ester Methyl N-methyltetrahydronicotinate Methyl 1,2,5,6-tetrahydro-1-methylnicotinate 5-22-01-00322 (Beilstein Handbook Reference) Methyl N-methyl-1,2,5,6-tetrahydronicotinate N-Methyltetrahydronicotinic acid, methyl ester methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate NICOTINICACID,1,2,5,6-TETRAHYDRO-1-METHYL-,METHYLESTER 1-Methyl-delta(sup 3,4)tetrahydro-3-pyridinecarboxylate 1,2,5,6-Tetrahydro-1-methylnicotinic acid, methyl ester methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate Nicotinic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester N-Methyltetrahydropyridine-beta-carboxylic acid methyl ester 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic acid methyl 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid Methyl Ester 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic acid methyl ester 1-Methyl-1,2,5,6-tertrahydro-pyridine-3-carboxylicacid methyl ester 3-Pyridinecarboxylicacid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester
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CAS | 63-75-2
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EINECS | 200-565-5 |
Methyl 1,2,5,6-tetrahydro-1-methylnicotinate - Physico-chemical Properties
Molecular Formula | C8H13NO2
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Molar Mass | 155.19 |
Density | 1.0504 g/cm3 (20 ºC) |
Boling Point | 209℃ |
Flash Point | 81.1°C |
Solubility | Soluble in water. |
Vapor Presure | 0.208mmHg at 25°C |
Appearance | Powder |
Color | Oily liquid |
pKa | 6.84(at 25℃) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.4860 (589.3 nm 20℃ |
MDL | MFCD00039041 |
Methyl 1,2,5,6-tetrahydro-1-methylnicotinate - Risk and Safety
Toxicity | LD50 in mice, dogs (mg/kg): 100, 5 s.c. (Burrows) |
Methyl 1,2,5,6-tetrahydro-1-methylnicotinate - Reference
Reference Show more | 1. Wang Hao, Luo Zhiqiang, Li Mengwei et al. Absorption and metabolism of simotang oral liquid in rats [J]. Chinese patent medicine 2018 040(003):718-722. 2. Cao Lina, Zhang Jianhao, Wang Xiaoting, Wei Qiaoyun, Wang Yiyue, Yan Wenjing. Effect of high voltage electric field low temperature plasma on cold sterilization performance of Areca catechu packaging products [J]. Food and machinery, 2020,36(05):133-139 193. 3. Fan Sufang, Ma Junmei, Liu Min, et al. Determination of 15 toxic alkaloids in foods by high performance liquid chromatography-tandem mass spectrometry [J]. Food Science, 2018, 39(22):290-295. |
Methyl 1,2,5,6-tetrahydro-1-methylnicotinate - Introduction
Arecoline, also known as Arecoline, is a nicotinic compound with the chemical name (1S,2R,6R,8S)-1,2,6,8-tetramethyldiazene. The following is a detailed introduction to Arecoline:
Nature:
-Appearance: The common form of Arecoline is a white or slightly yellowish crystalline solid, sometimes brown.
-Solubility: Soluble in ethanol, chloroform and ether, slightly soluble in water.
Use:
-Drugs: Arecoline is commonly used in drugs, with analgesic and dispel Oral odor.
-Tobacco: Arecoline is one of the most important alkaloids in tobacco, which can bring some excitement.
Preparation Method:
Arecoline can be obtained by two main preparation methods:
-extraction from areca nut: processing and extracting the fruit of areca nut, and then obtaining Arecoline through appropriate purification process.
-obtained by chemical synthesis: Arecoline is obtained by chemical reaction.
Safety Information:
Arecoline has a certain toxicity, need to pay attention to safe use.
-toxicity: Arecoline has certain toxicity to human body, excessive intake may cause poisoning symptoms such as nausea, vomiting, dizziness, tachycardia, etc. Long-term heavy use can also lead to addiction and health problems.
-Restrictions on Use: Arecoline is listed as a restricted or prohibited substance in some countries and regions because of its potential harm to human health.
Last Update:2024-04-09 19:05:02